Hydrochloride (MPTP-HCI, CAS Number: 23007854), Dopamine Hydrochloride (DA-HCI, CAS Number: 62-31-7), and Homovanillic Acid (HVA, CAS Number: 306-08-1) were purchased from Sigma-Aldrich (U.
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenylpyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Oiethyldithiocarbamate potentiates the neurotoxicity of in vivo 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
and of in vitro l-methyl-4-phenylpyridinium.
Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Acetyl-L-carnitine prevents total body hydroxyl free radical and uric acid production induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
(MPTP) in the rat.
1] have neurotrophic and neuroprotective actions against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
(MPTP)- or [beta]-amyloid-induced neuronal cell death.
An Orally Active Metalloporphyrin Protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Neurotoxicity in vivo.
Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Permanent human parkinsonism due to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
(MPTP): seven cases.