Also called allelomorph) of the 5-HTTLPR
gene smiled or laughed more when looking at funny comics or amusing film clips, compared to those with long versions of the gene.
Study participants with two short 5-HTTLPR
alleles were found to be most unhappy in their marriages when there was a lot of negative emotion, such as anger and contempt, and most happy when there was positive emotion, such as humor and affection.
Among those with the heterozygous 5-HTTLPR
genotype, children in treated families had less substance use at followup compared with children of the control families (Brody et al.
Simultaneous genotyping of four functional loci of human SLC6A4, with a reappraisal of 5-HTTLPR
They showed that decision-making is affected by variation in the serotonin transporter gene, at a region known as the 5-HTTLPR
, which has previously been reported to affect the response of the amygdala and is
Influence of 5-HTTLPR
and TPH variants on illness time course in mood disorders.
genetic marker is commonly reported in three forms based on allele length: L/L (two long alleles), S/L (one long and one short allele), and S/S (two short alleles).
As suggested by these studies of a possible relationship between OCD and the "l" allele, our group analyzed the 5-HTTLPR
polymorphism in Mexican OCD patients using a case-control methodology.
Association of the 5-HTTLPR
genotype and unipolar depression: a metaanalysis.
ADH1B*1, ADH1C*2, DRD2 (-141C Ins), and 5-HTTLPR
are associated with alcoholism in Mexican American men living in Los Angeles.
published another PCR study on 5-HTTLPR
, a common polymorphism within the promoter region of the serotonin transporter gene LSC6A4 and its relationship to liver fire flaming upward.
Two studies found that individuals with long (l) forms of the 5-HTTLPR
genotype (or l/l genotype) demonstrated increased intensity dependence [30-31], whereas the third study found that individuals with the l/l genotype demonstrated decreased intensity dependence .