Excess cholinergic stimulation with the use of AChEIs may lead to transitory nausea, vomiting, dizziness, insomnia and diarrhoea.
AChEIs may potentially have vagotonic effects on heart rate (i.
The latter consists of the use of AChEIs or memantine on their own or in combination followed by antidepressant, antipsychotic or other medication as indicated.
As well as medicine, AChEIs are a widely used class of insecticides (Finkelstein et al.
why we don't recommend using off-label AChEIs as a "first choice" augmentation strategy in schizophrenia patients at this time
In 2000, Cummings (3) summarized evidence from case reports and small studies that AChEIs were useful in treating neuropsychiatric conditions other than AD (Table 1).
5) Thus, broad-based cognitive enhancers such as AChEIs may be necessary for general use in this illness.
Concurrent use of anticholinergics and AChEIs is fairly common in clinical practice but is rarely appropriate because of pharmacologic antagonism.
Similarly, a study of pharmacy claims for AChEIs among 557 Medicaid beneficiaries aged [greater than or equal to]50 found that 35% of patients taking AChEIs also received at least 1 anticholinergic drug.
Interaction of antiparkinsonian medications with AChEIs could limit the efficacy of either drug when treating comorbid AD and Parkinson's disease (PD), (5) although in practice, clinical deterioration of parkinsonism has not been reported.