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References in periodicals archive ?
Because only Cu and V showed significant vasoconstrictor activity, we determined whether or not Cu and V could activate ERK1/2 and p38 MAPK.
Both R5 gp120 and X4 gp120 activate the MAP kinases p38 and c-Jun amino terminal kinase/stress-activated protein kinase (JNK/SAPK), though it is unclear whether a third member of the MAPK family, extracellular regulated kinase (ERK 1/2), is activated.
Kleeberger speculates that ozone initially injures cells in the lungs, inducing the release of molecules that activate TLR4 and create more damage through an immune reaction.
Although troglitazone is now off the market due to its hepatotoxicity, other thiazolidinediones that activate PPAR[gamma] are currently used as antidiabetic agents.
The new Activate version brings a number of new features that have been asked for by our existing customers, including instant enterprise access search, mobile interfaces, BYOD integration and more.
The p38 and ERK MAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV light.
Certain pesticides recently have been reported to activate MAP kinase signaling pathways in a mammalian prostate cancer cell line (34).
Previously, we found that heavy metals that can affect the immune system, such as cadmium, inorganic mercury, and organotin compounds, activate MAPKs in CCRF-CEM human lymphoblastoid cells prior to the development of apoptosis (12,13,22).
As in the current study, investigators could harvest macrophages, artificially activate them, and transplant them into damaged spinal cords or other injured CNS sites.