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Related to ADA-SCID: Adenosine deaminase deficiency
ADA-SCIDSevere Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Negative, Nk Cell-Negative, Due to Adenosine Deaminase Deficiency
References in periodicals archive ?
The current phase I/II study treated eight ADA-SCID children (ages 7-67 months) with HSC conditioned with busulfan, a treatment that helps with the engraftment process.
ADA-SCID is treated through a bone marrow transplant from the parent with the best immunologic match or by injections of purified ADA enzyme.
Alessandro Aiuti, MD and colleagues from the San Raffaele Telethon Institute for Gene Therapy, Italy; the University of Siena, Italy; the University of Turin, Italy; and the Hadassah University Hospital, Jerusalem exposed bone marrow calls from two ADA-SCID patients to retroviruses.