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ADAS-cog |
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| ? References in periodicals archive |
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In a meta-analysis of 10
randomized, double-blinded, placebo-controlled trials of approved
Alzheimer's disease drugs, published in 2006(1), treatment with
these drugs produced an average ADAS-cog improvement over placebo of 2. The abstract also reaffirms
earlier findings from the Cape Cod Memory Study that subjects'
BIS-AD measurement correlates with MMSE and ADAS-cog at baseline when
subjects first enter the study, further supporting the notion of a
learning effect. This will cover a
statistically significant improvement of ADAS-cog score over placebo
demonstrated by the 15mg twice daily group at times following 12 weeks
of treatment. |
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