Also found in: Medical.
AFB1Aflatoxin B1
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When these contaminated foods are eaten, AFB1 is broken down in the liver to a deadly carcinogenic product that binds to and mutates DNA.
31) Here, residents are unavoidably exposed to high AFB1 levels, and suffer high mortality rates due to liver cancer.
recorded complete cessation of egg production with follicular atresia in egg type breeders which were fed with AFB1 for three weeks.
AFB1 is also biotransformed by P450 enzymes to yield an electrophilic epoxide, which attacks DNA to initiate hepatotoxicity and genotoxicity (Eaton and Gallagher, 1994) via oxidative damage (Kodama et al.
AFB1, silibin, collagen ase type VI, dexamethasone, insulin and [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] (MTT) were purchased from Sigma Chem.
Studies on production performance and toxin residues in tissues and eggs of layer chickens fed on diets with various concentrations of aflatoxin AFB1.
e) Average daily aflatoxin intake was estimated based on AFB1 contamination levels in Czech maize, multiplied by average daily maize consumption in Eastern Europe.
AFB1 inhibits both DNA and RNA synthesis (Butler and Neal, 1977).