AIB1 - What does AIB1 stand for? The Free Dictionary
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|AIB1||Amplified in Breast Cancer 1|
References in periodicals archive
In studies involving a range of breast cancer cell lines, through miR-17-5p inhibiting translation, AIB1
expression was reportedly downregulated.
Overexpression of the steroid receptor coactivator AIB1
in breast cancer correlates with the absence of estrogen and progesterone receptors and positivity for p53 and HER2/neu.
In contrast, AIB1
has been associated with poor outcome on tamoxifen in HER2-amplified breast cancer because HER2 activates AIB1
and enhances the agonist effects of tamoxifen [33,34].