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AIF1Allograft Inflammatory Factor 1
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Several single nucleotide polymorphisms have been identified in the AIF1 gene.
Single nucleotide polymorphism within the AIF1 gene was genotyped using Taqman realtime polymerase chain reaction genotyping assay (Real-Time polymerase chain reaction; Applied Biosystems, USA) per manufacturer's instruction.
Specifically it translocates the AIF1 protein into the nucleus of the cell, causes chromatin condensation and DNA degradation, and leads to the cell's death.