ALK


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AcronymDefinition
ALKAutomatisierte Liegenschaftskarte
ALKAnti-Lift Kit (Subaru suspension system)
ALKAllergologisk Laboratorium København (Allergological Laboratory of Copenhagen)
ALKAssociation Languedocienne de Kyudo (French; Japanese archery association)
ALKAlaska Air Group, Inc. (stock symbol)
ALKAlkohol (German: alcohol)
ALKAnaplastic Lymphoma Kinase
ALKSrilankan Airlines (ICAO code)
ALKActivin Receptor-Like Kinase
ALKAutomated Limellar Keratoplasty (Surgical Procedure)
ALKAlkaline
ALKAlkylation
References in periodicals archive ?
So it appears that ALK can give cells a growth advantage in contexts as diverse as human cancers and developing fruit flies," added Gould.
The abnormality in ALK that arises in NSCLC is not, strictly speaking, a mutation rather, it results from a chromosomal rearrangement, in which the structure of a chromosome - the scaffolding of genetic material - is altered.
Assays like our Insight ALK Screen are important advancements in this evolving cancer landscape.
GenASIs Scan & Analysis offers clinicians a way to automatically perform genetic analysis on tissue samples, stained with the Abbott ALK[TM] probe kit, and identify the ALK gene rearrangement.
Chugai Pharmaceutical's selective ALK inhibitor CH5424802 produced an overall response rate of 85%, including 3 complete responses and 36 partial responses among 46 patients with advanced or metastatic ALK-positive NSCLC previously treated with one or more alemotherapies, but not with ALK inhibitors.
Several methods are available to detect ALK rearrangements, including break-apart fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), and reverse transcription-polymerase chain reaction (RT-PCR).
The ALK gene promotes lung cancer by encoding the production of ALK protein, an enzyme that is critical for the growth and development of cancer cells.
GenASIs further adds the ability to perform "walk away" automated genetic tissue scanning for ALK using an 81 slide continues scanning robot.
The third poster at ECC2015 reported results from a pilot study demonstrating the high sensitivity and specificity of IHC as a screening tool for ALK rearrangement.
The advanced courses are based on the basic courses and are aimed at ALK employees with practical experience of at least 18 months and a lot of customer contact or for ALK employees with managerial responsibilities.
para]]"FDA approval of the VENTANA ALK (D5F3) CDx Assay is a tremendous accomplishment," says Mary Padilla, MD Senior Director of Pathology and Medical Director for Ventana Companion Diagnostics.
The ALK gene is activated through chromosomal rearrangements, most notably with echinoderm microtubuleassociated proteinlike 4 (EML4) forming an aberrant fusion gene.