AM PEFA Small Decline in Morning Peak Expiratory Flow
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Onset of effect was evaluated as change in daily AM PEF from day of randomization.
Study medication was self-administered following the AM PEF rate measurement and at bedtime following the PM PEF rate measurement.
A significant treatment benefit in the AM PEF rate was achieved with salmeterol therapy and was maintained throughout the study period to produce a significant overall improvement compared with placebo (P [is less than] .