AOSLOAdaptive Optics Scanning Laser Ophthalmoscope
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Duncan commented, "We are extremely encouraged by the photoreceptor preserving effect of NT-501 seen in this study as well as the usefulness of AOSLO as a diagnostic tool for retinitis pigmentosa progression.
Paul Sieving, MD, PhD, Director of the National Eye Institute and Principal Investigator of Neurotech's Phase 1 study of NT-501 in RP commented, "These results suggest that AOSLO may play a meaningful role in the early assessment of photoreceptor loss due to retinitis pigmentosa well before serious functional loss is detected by standard measures of visual function, and that NT-501 may play an important neuroprotective role.
In order to bring the AOSLO to London, Mr Michaelides and the team at Moorfields and UCL Institute of Ophthalmology acquired a grant of 250,000 [pounds sterling] from the Wellcome Trust to build the machine.
The hope for the AOSLO is that it will lead to earlier disease detection and provide better insight into disease pathogenesis.