APD90Action Potential Duration at 90%
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In both groups, APD90 and APD50 decreased as stimulation frequency increased.
The major findings of our study are as follows: (i) Electrophysiological changes in DM group included prolonged IACT and increased AERPD; (ii) Increased inducibility of AF and LA interstitial fibrosis are evident and may constitute a substrate for the development of AF; (iii) APD90 and APD50 of atrial myocytes were prolonged in diabetic rabbits.
Changes in APD90 and APD50 in cells from both groups Variables Control (n=10) DM (n=10) 60 bpm APD90, ms 140.