integerrima possesses significant anti-asthmatic activity which may be attributed to reduction in TNF-[alpha], IL-4, and IL-5 expression levels, and increase in AQP1 and AQP5 expression levels.
AQP1 and AQP5 contribute in the formation of major path for water transport by osmosis between capillary compartments and airspace (Chen et al.
Effect of Citrullus colocynthis and Insulin Administration on mRNA Expression of AQP5 in Salivary Gland of Diabetic Rats
Diabetic rats showed significant downregulation in mRNA expression of AQP5 in salivary gland when compared with normal group.
All individuals who have inherited an AQP5
mutation were present with this rare skin condition.
Yapilan yeni arastirmalarda ise AQP5
mRNA ve protein disavurumu keratokonuslu ve normal goz kornealarinda esit miktarda bulunmustur.
A similar mechanism apparently controls AQP5
function in lung epithelial cells and various secretory glands.
3] selectivities of AQP1, AQP4, AQP5
, AmtB, and RhAG.
Figure 1 shows that AQP3, AQP4, and AQP5 are all expressed in secretory glands, such as salivary and lacrimal glands.
Other groups have observed differences in AQP5 localization between SS patients and controls, using histological staining and centrifugal fractionation.
A role for AQP5
in activation of TRPV4 by hypotonicity: concerted involvement of AQP5
and TRPV4 in regulation of cell volume recovery.
As for anurans, physiological and immunohistological studies unveiled the possible functions of AQP2, AQP3, AQP5
, and AQP6 (AQPa2) in the osmoregulatory organs (Kubota et al.