ATSIC: Well, strictly speaking, I'm an ASO4
and it's not my right to comment on it anyway.
5 ml dose IM Adjuvant (6) ASO4
which Aluminium includes 3-O desacyl- hydroxy- 4'monophosphoryl phosphate lipid A and sulphate aluminium salt Duration of proven efficacy (3) Proven efficacy Proven studied up to efficacy studied 4.
Aluminyum tuzlari ile birlestirilerek ASO4
olarak tanimlanan bu adjuvan hepatit B asisinda (Fendrix[TM], GSK Biologics) kullanilmaktadir (35).
Recent studies suggest that the added power of GSK's innovative ASO4
adjuvant provides Cervarix with enhanced immune responses.
The vaccine consists of purified L1 VLPs of HPV types 16/18 formulated on an ASO4
adjuvant comprising 500[MU]g of aluminium hydroxide and 50[MU]g of 3-dacylated monophosphoryl Lipid A.
It has a proprietary adjuvant ASO4
comprising of 500 [micro]g of aluminium hydroxide and 50 [micro]g of 3-deacylated monophosphoryl lipid A which induced a stronger and sustained immune response (18).
Commercially available HPV vaccines Vaccine Gardasil Cervarix HPV types 6, 11, 16, 18 16, 18 Dosing schedule 0, 2, 6 months 0, 1, 6 months Adjuvant AAHS (amorphous ASO4
(aluminum aluminum hydroxide + MPL) hydroxyphosphate sulfate) VLP preparation Yeast Insect cell system Efficacy against disease caused by HPV types in the vaccine 100% (11) 98.