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In light of these findings, the patient was placed on empiric
piperacillin/tazobactam and amphotericin B lipid complex to cover
bacterial skull base osteomyelitis and invasive fungal sinusitis. She received several courses of antibiotics for extended
periods including imipenem, amikacin, piperacillin/tazobactam,
vancomycin, amphotericin B lipid complex, fluconazole, ciprofloxacin,
and tobramycin. Results of the study, titled "A Randomized, Double-Blind
Comparative Trial Evaluating the Safety of Liposomal Amphotericin B
Versus Amphotericin B Lipid Complex in the Empirical Treatment of
Febrile Neutropenia," were published in the journal Clinical
Infectious Diseases (volume 31, number 5: 1155-63). |
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