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ARB |
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? References in periodicals archive |
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Hwyda Arafat at the Kimmel Cancer Center at Thomas Jefferson
University recently showed that angiotensin I-converting enzyme (ACE)
was active in tumors from patients with pancreatic cancer, and that ACE
inhibitors and angiotensin II receptor blockers (ARBs) blocked the
production of a potent angiogenesis factor called VEGF in pancreatic
cancer cell lines. Tokyo, Japan, July 5, 2006 - (JCN) - Astellas Pharma and Nippon
Boehringer Ingelheim have filed a joint application for an additional
indication of Micardis, an angiotensin II receptor blocker, with the
Ministry of Health, Labor and Welfare. Most patients in the clinical trial supporting
effectiveness, referred to as A-HeFT, received, in addition to BiDil or
placebo, a loop diuretic, an angiotensin converting enzyme inhibitor or
an angiotensin II receptor blocker, and a beta blocker, and many also
received a cardiac glycoside or an aldosterone antagonist. |
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