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Clinically, patients with cerebellar disease and anterior lobe atrophy show antero-posterior sway, often with a spontaneous high-frequency body tremor of around 3 Hz (Diener et al. In contrast, patients with midline cerebellar disorders, such as anterior lobe atrophy, often show hypermetric postural responses in which each EMG burst is too large and too long, resulting in falls in the direction opposite to the direction of perturbation. 2) Anterior lobe (paleocerebellum or spinocerebellum) and midline disease impairs lower-limb coordination, equilibrium responses, and head and trunk synergy, whereas lateral lobe disease chiefly affects limb coordination. |
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