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As an antiepilepsy drug, topiramate limits over-stimulation of brain cells. The effectiveness of Gabitril when added to an existing regimen of at least one other antiepilepsy drug (adjunctive therapy) was examined in three multi-center, double-blind, placebo-controlled, parallel group clinical trials in 769 patients with refractory partial seizures, as well as two placebo-controlled cross-over studies in 90 patients. ``Results of our research program demonstrate that tiagabine, when added to antiepilepsy drug (AED) regimens, can improve seizure control in patients with partial seizures,'' says Bruce Wallin, M. |
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