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III] specific A kinase (PRKA) anchor AKAP5 Signal transduction protein 5 Ataxin 1 ATXN1 RNA binding CD22 antigen CD22 Cell adhesion Connective tissue CTGF Regulation of cell growth factor growth, cell adhesion RNA, U70 small nucleolar RNU70 Unknown Integrin beta 1 binding ITGB1BP1 Cell adhesion protein 1 E2F transcription E2F1 [G. So the SCA8 repeat expansion makes a polyglutamine protein but in the opposite direction from the other gene that we knew was expressed in the CUG direction So the overall organization then of the SCA8 region is that there are two genes: the first gene ataxin 8 opposite strand ( Phosohorylation of Ataxin 3- implication for cellular localization and viability. |
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