| Acronym | Definition |
|---|
| AFS | Andrew File System |
| AFS | American Fisheries Society |
| AFS | American Foundry Society |
| AFS | American Field Service |
| AFS | AIRS (Atmospheric Information Retrieval System) Facility Subsystem |
| AFS | Adaptive Front-Lighting System (car safety feature) |
| AFS | Air Force Station |
| AFS | Available For Sale (securities) |
| AFS | Anti Fouling System (shipping) |
| AFS | American Foundrymen's Society |
| AFS | Armor For Sleep (band) |
| AFS | American Fern Society |
| AFS | American Filtration & Separations Society |
| AFS | Annual Financial Statements |
| AFS | American Folklore Society |
| AFS | Asian Fisheries Society |
| AFS | Australian Forestry Standard |
| AFS | American Fertility Society (now American Society for Reproductive Medicine) |
| AFS | Auxiliary Fire Service |
| AFS | Allergic Fungal Sinusitis |
| AFS | Air Force Specialty |
| AFS | Association of Former Students (Texas A&M University) |
| AFS | Air Flow Sensor |
| AFS | Active Front Steering (automotive) |
| AFS | Alcohol Focus Scotland |
| AFS | Aboriginal Fisheries Strategy (Canada) |
| AFS | Atomic Fluorescence Spectroscopy |
| AFS | Active Federal Service |
| AFS | aeronautical fixed service (US DoD) |
| AFS | Agence Française du Sang |
| AFS | Association of Football Statisticians (soccer) |
| AFS | Automatic Flight System |
| AFS | Advanced Front-Lighting System (automobiles) |
| AFS | Auto Flight System |
| AFS | Apple Financial Services |
| AFS | Adult and Family Services Division (Oregon DHS) |
| AFS | Advanced Financial Services, Inc. (Newport, RI) |
| AFS | Akademska Folklorna Skupina |
| AFS | Air Force Standard |
| AFS | Air Force System |
| AFS | American Fuchsia Society |
| AFS | Advanced Flight Simulator |
| AFS | Combat Store Ship |
| AFS | Audio Frequency Shift |
| AFS | Automated Financial System |
| AFS | Active Fleet (Surface) Ship |
| AFS | Atomic Frequency Standard |
| AFS | Association Francaise de Stérilisation (Lyon, France) |
| AFS | American Funds Service Company |
| AFS | Application For Service |
| AFS | Australian Fisheries Service |
| AFS | Angel Flight Samaritans |
| AFS | Autogenic Feedback System |
| AFS | Assisted Filing Service |
| AFS | Aerial Film Speed |
| AFS | Auxiliary Feedwater System |
| AFS | American Food Service |
| AFS | Adaptive Frequency Sampling |
| AFS | Arab Federation of Shipping |
| AFS | Amniotic Fluid-Derived Stem Cell |
| AFS | Authentication File System (IBM) |
| AFS | Flight Standard Service (US FAA) |
| AFS | Armed Forces Sports (US DoD) |
| AFS | American Flagship Service |
| AFS | Agency Filing Scheme |
| AFS | Active File Set |
| AFS | Atlanta's Finest Staffing (employment/recruiter agency) |
| AFS | Away from Station |
| AFS | Advanced Filter Solutions, Inc. |
| AFS | Action Freight Services |
| AFS | Air Force Supplement |
| AFS | ASIC Functional Specification |
| AFS | Army Fire Support |
| AFS | Allen Freight Services, Inc (Jacksonville, FL) |
| AFS | Automotive Financial Services Pty Ltd (Australia) |
| AFS | AppleShare File System |
| AFS | Automatic Fuel Dispensing |
| AFS | Agency Field Specialist |
| AFS | Away From Screen |
| AFS | Aggressive French Speakers (pro-gaming clan) |
| AFS | Australian Flag Society |
| AFS | Alternative Filing System |
| AFS | Alternative Format Syntax |
| AFS | Auditable Financial Statement |
| AFS | Autofocus Subassembly |
| AFS | Associated Freight Services (London, UK) |
| AFS | Assembly Floor Sheet |
| AFS | Automatic Frequency Standard |
| AFS | Air Fire Support |
| AFS | Accommodation and Food Services (various locations) |
| AFS | Automated Firearms System (California) |
| AFS | Anglo French Services (language training company; Paris, France; est. 1988) |
| AFS | Association Française de Sémiotique (French: French Semiotics Association) |
| AFS | Agreement for Services (various organizations) |
| AFS | Allied Free Sentients (gaming) |
| AFS | Association Française de Sociologie (French: French Sociology Association; est. 2002) |
| AFS | Association France Spondylarthrites (French: Spondylitis Association of France) |
| AFS | Attestation de Formation Spécialisée (French: Certificate of Specialized Training; various universities) |