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BCL2

   Also found in: Medical, Wikipedia 0.01 sec.
AcronymDefinition
BCL2B-Cell CLL/Lymphoma 2


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? References in periodicals archive
2] also induces the apoptotic regulators BCL2 and BAG1 in cultured breast cancer cells (Perillo et al.
The genes most predictive of overall survival in DLBCL were LMO2, BCL6, FN1, CCND2, SCYA3 and BCL2.
The t(14;18)(q32;q21) translocation results in the juxtaposition of the BCL2 gene on chromosome 18q21 with the immunoglobulin heavy chain (IGH) gene on chromosome 14q32, causing overexpression of BCL2, which maintains the neoplastic proliferation of B-cells.
 
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