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Smaller numbers of members of other unions, including the Communication, Energy and Paperworkers [CEP], BCNU, OPEU, International Brotherhood of Electrical Workers, Pulp and Paper Workers, and IWA, also struck.
In the first clinical trial, which included 222 patients at 27 medical centers, polymers containing the anticancer agent carmustine, or BCNU, "significantly prolonged patient survival," says Brem.
BCNU causes pulmonary fibrosis: lungs harden, with dry cough, fever, difficult breathing and cyanosis in 20 to 30 percent of patients.
Avichai Shimoni (Chaim Sheba Medical Center, Tel Hashomer, Israel) presented an update with longer follow-up time from a multi-center, prospective randomized study, for which he reported that ZEVALIN administered in combination with BCNU, etoposide, cytarabine (Ara-C), melphalan (BEAM) therapy -- Z-BEAM -- resulted in a 91% two-year overall survival (OS) rate in patients with refractory/relapsed aggressive lymphoma, versus a 62% OS rate in patients administered BEAM alone (p=0.
Potentialisation of BCNU antitumor efficacy by 9-substituted O6 benzylguanines.
As a Gliadel Implant dissolves, BCNU is delivered directly to the site once occupied by the tumor, providing site-specific chemotherapy to target any remaining tumor cells.
Campaign officer with the BCNU Shirely Ross said nurse/patient ratios would be a "very sticky issue" at the bargaining table.
These therapies included radiation therapy, high-dose tamoxifen, and a craniotomy for tumor resection and placement of BCNU wafers.
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- BCNU, Etoposide, Ara-C, Melphalan