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Still, BDSI is taking the precaution of developing a Risk Minimization Action Plan, or RiskMAP, for its fentanyl patch. According to the terms of the license, Accentia will pay BDSI a running royalty of 12-14% on net sales in the United States. Sara Krause-Elsmore, PhD, a research scientist at BDSI who leads the Bioral Non-Steroidal Anti-Inflammatory Drug (NSAID) Cochleate Program, stated; "Taking anti-inflammatories, such as aspirin, for extended periods of time to combat chronic inflammation leads to serious problems in the digestive tract, like bleeding and ulcers. |
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