This part of the study compared the five cases of allogeneic ICT and the six cases of autologous ICT that employed the BIIM.
In modifying the KIIM (10, 11), we eliminated the in situ cooling system (33) because it was designed to minimize warm ischemic injury after cardiac arrest, and the BIIM was developed for brain-dead donors without warm ischemic injury.
In the second part, differences between allogeneic and autologous ICT were investigated using cases that implemented the BIIM.
Multivariate logistic regression analysis revealed that the BIIM, our current isolation protocol, was an independent predictor of success.
Multivariate logistic regression analysis revealed that only the BIIM had a significant impact on successful islet isolation with brain-dead donors.