BLNKB-Cell Linker Protein
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Conley hypothesized that defects in BLNK might be responsible for immunodeficiency in some patients who had no B cells but who did not have defects in any of the genes that have been shown to cause immunodeficiency.
Mutations in BLNK were found in a sample of DNA from a 20-year-old male, with agammaglobulinemia and no B-cells.
2 /PRNewswire/ -- Scientists have discovered that a linker protein called BLNK (B-cell linker) is essential for normal development of the immune system.