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1) A rise in baseline levels of serum myeloma monoclonal proteins or urine Bence Jones protein may signify a recurrence of the primary or the onset of multiple myeloma. In addition, the Bence Jones protein may go undetected in the urine when immunofixation electrophoresis is negative and the patient is not symptomatic. CT and measurements of serum immunoglobulin and urinary Bence Jones protein levels may be useful in detecting recurrence or conversion to multiple myeloma. |
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