Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis.
Deletion of beta-2-microglobulin ameliorates spinal cord lesion load and promotes recovery of brainstem NAA levels in a murine model of multiple sclerosis.
In this study an attempt was made to correlate plasma levels of immune activation markers neopterin, beta-2-microglobulin
([beta]2M), and soluble tumour necrosis factor alpha-receptor type I (sTNF[alpha]-RI) with the presence of active TB in HIV-infected and uninfected individuals, and to study the changes following anti-tuberculosis treatment (ATT).
In this continuing study, our new goal was to compare the diagnostic potential of beta-2-microglobulin
($2M) with that of six other tumor antigens for breast, ovarian, testicular and prostate cancers.
Ashcroft and Radford are studying beta-2-microglobulin
to try to understand how it forms such fibrils which accumulate in the joints of dialysis patients and which are associated with dialysis-related amyloidosis.
Attempts are being made to develop membranes that can more efficiently remove beta-2-microglobulin
from the blood during hemodialysis (NKF, 2003).
This is true of PSA as well as for CEA for colon cancer surgery follow-up, beta-2-microglobulin
for multiple myeloma, or HCG for testicular carcinoma or choriocarcinoma.
Online HDF is a "convective" based renal replacement therapy offering improved removal of uremic toxins, in particular middle-molecular weight toxins such as beta-2-microglobulin
Evaluation of renal tubular damage in liver cirrhosis by urinary enzymes and beta-2-microglobulin
is a low-molecular-weight (11.
Evaluation showed a statistically significant drop of the pre-dialysis level of the toxin beta-2-microglobulin
(Beta(2)m) compared to baseline levels.
COMPARED WITH FOURTEEN OTHER ANTIGENS FOR THE DETECTION OF BREAST CANCER