sup] Bone marrow stromal cells
(BMSCs) can be easily obtained from patients themselves without ethical or immunological problems.
Najafzadeh, "Co-transplantation of bone marrow stromal cells
with schwann cells evokes mechanical allodynia in the contusion model of spinal cord injury in rats," Cell Journal, vol.
Silberstein, "Human bone marrow stromal cells
express a distinct set of biologically functional chemokine receptors," Stem Cells, vol.
Wu, "Intravenously transplanted bone marrow stromal cells
promote recovery of lower urinary tract function in rats with complete spinal cord injury," Spinal Cord, vol.
The frequency, growth kinetics, and osteogenic/adipogenic differentiation properties of canine bone marrow stromal cells
Keywords: Panax notoginseng saponins Bone marrow stromal cells
Wnt/[beta]-catenin signaling pathway Osteoprotegerin (OPG) Receptor activator of NF-KB ligand (RANKL)
The NIH Bone Marrow Stromal Cell
Transplantation Center completed the evaluation in August with a conclusion that CaridianBCT's technology successfully reproduced considerable quantities of adult BMSCs in an automated process in functionally closed environment.
LTC-IC assay with limiting dilution is relatively easier than the other LTC-IC assays, since the preprepared murine bone marrow stromal cell
line plates can be used in five weeks, and counting CFUs is easier than counting CAFCs.
Recently, subarachnoid injection has been reported as a minimally invasive method of transplantation of bone marrow stromal cells
for spinal cord injury.
Quarto R, Mastrogiacomo M, Cancedda R, Kutepov SM, Mukhachev V, Lavroukov A, Kon E, Marcacci M 2001 Repair of large bone defects with the use of autologous bone marrow stromal cells
New England Journal of Medicine 344 385-386
2003, showing that surface-expressed RANKL protein on human bone marrow stromal cells
, isolated by flow cytometry, was substantially increased in cells from post-menopausal women, as compared with pre-menopausal women, as well as with estrogen-treated post-menopausal women--demonstrate that estrogen can regulate RANKL expression on bone marrow stromal cells
, although the studies do not demonstrate if this is a direct or indirect effect.