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The protocol used to monitor older children can be modeled on the paradigm used for adults, but for very young children it might be necessary to rely only on objective tests, such as otoacoustic emissions testing, tympanometry, and auditory brainstem-evoked response testing. Techniques such as electroencephalography (EEG), event-related potentials (ERP), and brainstem-evoked response (BSER) all share a common approach to cortical electrophysiology -- scalp electrodes are used to detect electrical activity generated by the brain. It is difficult to think of many factors other than gentamicin toxicity that could have caused these patients' bilateral peripheral vestibular loss, but we nevertheless carefully ruled out other causes by performing extensive immunologic and serologic testing, intracranial imaging, advanced brainstem-evoked response audiometry, and vestibular testing. |
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