Nine of the 39 isolates were randomly selected for PCR, performed with the S3/AS3 primer pairs, which are specific to CA24v.
The nucleotide sequences of the protease 3C region among the 14 Korean isolates of CA24v were 98.
We also sequenced capsid protein VP1 region of CA24v isolates from two of our patients.
Our study demonstrated that CA24v was the causative agent of the South Korean outbreak of AHC in the summer of 2002.
An outbreak of AHC attributable to CA24v was first recognized in Singapore in 1970; outbreaks have occurred periodically there since (12,13).