CADASIL


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AcronymDefinition
CADASILCerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
References in periodicals archive ?
Ischaemic cerebral vascular disease caused by vasculitis, antiphospholipid syndrome, CADASIL, leukoaraisosis, or MS should be kept in mind in the differential diagnosis of cerebral WMLs.
Clinical severity in CADASIL related to ultrastructural damage in white matter: In vivo study with diffusion tensor MRI.
6 years was reported in one database of 105 CADASIL patients.
Retiring in 1988 due to ill health, Jack later became concerned about the general worldwide lack of awareness surrounding CADASIL.
A genetic form of vascular dementia, CADASIL, has been discovered, and the mutant gene identified as Notch 3.
Blood vessels in CADASIL patients over-react to the hormone angiotensin II, which is part of an important system that regulates blood pressure.
5) Periventricular hyperintensities are seen even in asymptomatic patients, and CADASIL should be diagnosed with caution in its absence.
5) In the presence of these findings, it is sometimes possible to suspect CADASIL at the outset and to avoid, thereby, a false diagnosis of MS.
It is the result of a three-year battle by Mr Shields, of Thropton, Northumberland, who decided to devote the rest of his days to helping other sufferers after finding there was so little help around for victims of CADASIL, a hereditary migraine disease combined with small strokes which can cause memory loss.
CADASIL has not been described in South Africa, and we report on 5 South African patients with the condition.
20) However, our patient had no positive family history of cerebral ischaemic events, showed no signs of cognitive decline and, on brain MRI, multiple and confluent hyperintensities on T2 and FLAIR were not detectable, which is unusual for CADASIL and MELAS.
Therapath's focus is on research and development in the testing services for muscle biopsy, nerve biopsy with teased fiber analysis, ocular (including optic neurotis), skin epidermal nerve fiber density, sweat gland nerve fiber density, skin biopsy for CADASIL and other storage disorders as well as brain/spinal cord specimens.