19) The purpose of CAPIT was to establish international consensus on the assessment of PD patients enrolled in clinical cell transplantation protocols, so that results from different clinical trials could be compared and amalgamated.
The timed tests in CAPIT are pronation/supination of the hands, finger dexterity, hand/arm movement between two points, and a walking test.
The CAPIT protocol has recently been revised to make it more suitable as a common assessment program for all neurosurgical interventions in PD, not just transplantation trials.
As a practical complement to the CAPIT and CAPSIT-PD protocols, (6,19) this article provides more detailed guidelines, recommendations, and suggestions for the use of timed tests as complements to other measures in the clinical assessment of motor function in PD.
The hand/arm movement and walking tests are described and discussed as they appear in the new CAPSIT-PD, (6) whereas the pronation/supination and finger dexterity tests refer to the original CAPIT protocol.
One problem with the original timed tests according to CAPIT, as well as the walking test as it appears in CAPSIT-PD, is that no time limits have been set for their completion.
Originally, in CAPIT the time taken to complete 10 movement cycles was recorded, (19) whereas CAPSIT-PD recommends the number of movements completed in 20 seconds be recorded.
5) CAPIT and CAPSIT-PD advocate a 33% improvement in the UPDRS motor score as a criterion for dopaminergic responsiveness.