7,20,21) Table 2 summarizes the clinical distinctions between CCC (103 cases), EMEC (97 cases), and to a lesser extent, CCMEC (11 cases), based on cases culled from the literature and the cases reported in this article.
Therefore, our experience extends the reported data, in that CCC lacks myoepithelial differentiation and appears distinct from EMEC and CCMEC, which have "obligate" myoepithelial differentiation.
45) This characteristic has been cited as a reason why myoepithelium-rich tumors generally grow in a bulky lobulated fashion, rather than in an insidiously infiltrating pattern, as is seen here for EMEC and CCMEC.
8 70/M Parotid 2 CCMEC Previous LTF parotid tumor 28 y earlier ([dagger]) 9 63/M Palate 1.
The CCMEC was strongly positive for S100 as well as cytokeratin cocktail; calponin staining was light, and no staining for muscle-specific actin was observed.