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CCR9

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AcronymDefinition
CCR9C-C Chemokine Receptor 9 (gene)


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? References in periodicals archive
ChemoCentryx's lead compound, Traficet-EN, a specific CCR9 antagonist, is currently in a multi-national clinical trial, called PROTECT-1, in patients with moderate-to-severe Crohn's disease.
The chemokine receptor CCR9 appears to be selectively involved in the migration of T cells to the gut and likely will meet future drug development.
p-53-dependent benzene-induced decrease or increase Decrease Adcy6, ApoE, AQ1, B cell antigen receptor, Cam III, CCR9, E2F1, WT: decreased FATP4, Fscn1, GPCR (EB11), Ig kappa light chain, IgA, IgH, p53-KO: unchanged mur42, Pdk1, PPT-B, Prkm1, TP, TRBF1 Increase Adipose fatty acid binding protein, Adh-3, caspase-11, cyclin G1, WT: increased CYP7B1, EGFB-3, emp-1, FKBP23, c-fos, Hox-4.
 
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