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CD44Cluster of Differentiation 44
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CD44 (12-0441-81, eBioscience, USA) and CD73 (550257, BDBioscience, USA) were considered as mesenchymal stem cells markers and, CD45 (341071, BDbioscience, USA) and CD11b (110112-41, eBioscience, USA) as hematopoietic and macrophage markers.
Fluorescent reporter assays proved that CD44 acts as the target spot of micro ribonucleic acid 34-a for repression in post-transcription level.
The objective of the study was to determine the correlation between the non-invasive measurement of tumor aggressiveness via TIFP using DCE-MRI and immunohistochemical (IHC) staining CD44 expression.
CD44, but not l-selectin, is critically involved in leucocyte migration into the skin in a murine model of allergic dermatitis.
Discriminatory immunohistochemical staining of urothelial carcinoma in situ and non-neoplastic urothelium: an analysis of cytokeratin 20, p53, and CD44 antigens.
Expression of A and H blood-group and of CD44 antigens during chemical rat colonic carcinogenesis.
Effects of hyaluronate on CD44 expression of infiltrating cells in exudate of rat air pouch, induced by sensitization with lipopolysaccharide.
These cells were also strongly positive for markers such as twist family bHLH transcription factor (Twist), CD44, ATP binding cassette subfamily C member 1 (ABCC1), or ADAM metallopeptidase domain 17 (ADAM17).
It is considered that CD44 is involved in cell adhesion, cell activation, regulation of tumor growth, and apoptosis.
Based on our comparison of the metabolic profiles of human tissues and cancer cells, we suggest that curcumin might couple with CD44 and that curcumin-CD44() coupling at the cell membrane might have some blocking effect on the transport of glutamine into the cells, thus decreasing the glutamine content in the CD44() cells and inducing apoptosis.
Also reported was a large inverted component, the presence of small nests of urothelial cells in the stalk, and the strong staining for CK5 and CD44.