CFTR


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Related to CFTR: cystic fibrosis, CFTRI
AcronymDefinition
CFTRCystic Fibrosis Transmembrane Conductance Regulator
CFTRChemin de fer Touristique du Rhin (French railway association)
CFTRCentre de Formation du Transport Routier (French: Road Transport Training Center; Canada)
CFTRComité Français pour les Techniques Routières (French: French Committee for Road Engineering)
CFTRCystic Fibrosis Transmembrane Gene
CFTRCouncil for Tobacco Research
CFTRConsumers for Fair Telephone Rates
CFtrTransition Coupling Fault
CFTRCitizens for the Republic, Inc. (Alexandria, VA)
References in periodicals archive ?
Cystic fibrosis (CF), a genetic disease caused by mutations in the CFTR gene, is a life-limiting disease characterized by chronic bacterial airway infection and severe inflammation.
Mutation analysis: PCR amplification of exon10 and 17a of CFTR gene was performed using Gene Amp PCR System 9700 (Applied Biosystems, USA).
Twenty nanograms of each genomic DNA sample were used for PCR enrichment of CFTR targets by applying a custom AmpliSeq[TM] panel (Life Technologies).
38) The aqueous layer, which is composed of proteins, electrolytes, enzymes, metabolites and water (39) is principally produced by the lacrimal gland and accessory lacrimal glands, although recent evidence suggests a small proportion of electrolytes and water are secreted by the cornea and conjunctiva, via ion channels, (40) including CFTR (see Figure 2).
The remaining 77 mutations were tested biochemically in cells to determine the amount of damage sustained by the CFTR protein in each case.
Gross genomic rearrangements involving deletions in the CFTR gene: characterization of six new events from a large cohort of hitherto unidentified cystic fibrosis chromosomes and meta-analysis of the underlying mechanisms.
There are approximately 1250 known CFTR mutations, with homozygous [DELTA]F508 being the most common.
When the scientists exposed the mice to a bacterium called Pseudomonas aeruginosa that commonly infects cystic fibrosis patients, mice lacking a functional CFTR protein proved significantly more susceptible to it than normal mice.
We used dilutions of 1:2 for CAII, 1:400 for NHE3, 1:50 for CFTR, 1:100 for DRA, 1:200 for ATPase [alpha]1, 1:400 for ER[alpha], and 1:400 for ER[beta].
Genzyme Corporation today announced the commercial availability of cystic fibrosis (CF) gene sequencing -- a new diagnostic test that can detect approximately 98 percent of the more than 1,200 disease-causing mutations in the CFTR gene.
The CFTR gene is responsible for producing glutathione, as it makes the CFTR protein that exports glutathione.
CF manifests when a person receives a mutated copy of the CFTR gene from both parents.