CGRP


Also found in: Medical.
AcronymDefinition
CGRPCalcitonin Gene-Related Peptide
CGRPControlled Goods Registration Program
CGRPCalcitonin Gene-Related Product
CGRPPorcine Calcitonin Gene Related Peptide
CGRPCommon Hardware Reference Platform
CGRPCoolant Group (TARTAR)
CGRPChicken Gastrin-Releasing Peptide
References in periodicals archive ?
The license agreement, originally executed in July 2016, continues to provide Biohaven with exclusive global development and commercialization rights to rimegepant, BHV-3500 and related CGRP molecules, as well as related know-how and intellectual property.
org&rfr_dat=cr_pub%3dpubmed) more sensitive to CGRP  levels, and high CGRP triggers migraine-like headaches within hours.
This activity, in turn, irritates nerves in the blood vessels of the meninges--the membrane that covers the brain--and prompts the dilation of blood vessels and migraine pain through release of CGRP, serotonin, and other molecules.
VALENCIA, SPAIN -- In the lecture halls and corridors at the International Headache Congress, far and away the dominant topic of conversation was the latest highly promising data for the CGRP (calcitonin gene-related peptide)-inhibiting monoclonal antibodies being developed for migraine prophylaxis.
These are documented effects of CGRP from Susan Brain in 1985:
Furthermore, ECF pre-treatment significantly attenuated the ethanol-induced decrease in CGRP expression, which has a protective role against gastric ulceration.
22,23) However, AC187 is a potent and selective AMY antagonist (24) that has been shown to discriminate between CGRP and AMY receptors in transfected cells.
More relevant therapeutically, however, is an anti-migraine drug already on the market that inhibits a protein called CGRP that is triggered by TRPV1, producing an effect similar to that caused by blocking TRPV1.
Depolarization of nociceptive neurons causes the release of CGRP [58].
In separate groups of rats (n = 16), CGRP was extracted from the dorsal root ganglia (DRG) of the L5 and L6 roots and quantified by radioimmunoassay (RIA).
El efecto del movimiento dental experimental en las fibras nerviosas inmunorreactivas para CGRP y al producto proteico del gen (PGP) 9.
On the other hand giving PGE2, L-arginine or CGRP then restored the hyperemic and protective effects conveyed by the spice.