Between October 1999 and October 2000, we enrolled 601 pregnant women as part of the CHAMACOS
To look at the preliminary findings of the CHAMACOS
study, check out bit.
studies have also revealed links between flame retardant concentrations in mothers' blood and decreased fertility, lower birthweight babies and changes in thyroid hormone levels, even after controlling for exposure to pesticides and other environmental chemicals.
To explore relationships between prenatal OP exposure and birth outcomes and potential modification by the PON1 genotype and race/ethnicity, we pooled data from four previously published longitudinal studies--the CHAMACOS
, HOME, Columbia, and Mount Sinai cohorts.
, women who personally laundered agricultural work clothes had 2-42% significantly higher serum levels of DDT and HCH than women who did not, but this association was not significant after adjusting for living in Mexico, where DDT had been widely used (Bradman et al.
Because maternal pregnancy PBDE serum concentrations have previously shown associations with TSH in CHAMACOS
participants (Chevrier et al.
Table 1 presents maternal and child characteristics of the CHAMACOS
birth cohort by obesity status at 7 years of age.
Detailed methods about the CHAMACOS
study are described elsewhere (Eskenazi et al.
study is a community/university partnership.
PBDE serum concentrations in the CHAMACOS
population (Chevrier et al.
We also observed associations between maternal DAP levels during pregnancy, particularly dimethyl phosphates (DMs; resulting from exposure to DM pesticides), and CHAMACOS
2-year-olds' mental development as assessed on the Bayley Scales of Infant Development (Bayley 1993).
To understand the impact of the women's regional environment on these findings, they compared metabolite concentrations from the CHAMACOS
cohort with U.