CHDIChild Health and Development Institute (Farmington, CT)
CHDIClinton Hunter Development Initiative (sustainable development initiative; William J. Clinton Foundation; New York, NY)
CHDICure Huntington's Disease Initiative
CHDICancer Health Disparities Initiative (University of Wisconsin Carbone Cancer Center; Madison, WI)
References in periodicals archive ?
A pharmacodynamic biomarker could be an important contribution to our clinical development efforts, and we look forward to working with KineMed and CHDI to evaluate KineMed's biomarker platform in our Huntington's disease program," said Frank Bennett, Ph.
CHDI and its collaborators have developed a unique series of 20 ES cell lines from genetically modified mouse models that mimic aspects of Huntington's disease.
CHDI is dedicated to researching therapies that could help Huntington's disease patients and our team looks forward to the collaboration with Samaritan.
Over time, CHDI will be reimbursed for its support of Isis' program out of milestone payments received by Isis.
Following the successful start-up of their PPDI business, Du Pont is soon expected to bring CHDI to market.
George Yohrling, PhD, Director, Target Assessment at CHDI added, "This second phase of our collaboration with Galenea will focus on understanding whether there is a polyglutamine-length dependency to the observed synaptic alterations and on building a broad HD drug-discovery platform through the application of these novel findings.
As part of the collaboration CHDI will conduct pre-clinical studies on a Lundbeck investigative compound.
Evotec has long-term discovery alliances with partners including Bayer, Boehringer Ingelheim, CHDI, Genentech, Janssen Pharmaceuticals, MedImmune/AstraZeneca and Ono Pharmaceutical.
The application of KineMed's technology will provide us with unique insights into central nervous system disease pathophysiology," said Seung Kwak, PhD, Director, Target Biology at CHDI.
and supported by CHDI - demonstrate that a small interfering RNA (siRNA) targeting the huntingtin gene, when administered by intrastriatal infusion with convection-enhanced delivery (CED), results in widespread distribution of the siRNA and significant silencing of the huntingtin mRNA throughout the striatum.
CAMD Members: Abbott, Alliance for Aging Research, Alzheimer's Association, Alzheimer's Foundation of America, AstraZeneca Pharmaceuticals LP, Bristol-Myers Squibb Company, CHDI Foundation Inc, Eli Lilly and Company, F.