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CML-CP

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AcronymDefinition
CML-CPChronic Myelocytic Leukemia Cells in Chronic Phase


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Resistant or Intolerant Ph+ CML-CP and CML-AP: In chronic phase patients, the most commonly reported adverse drug reactions (>10%) were rash, pruritus, nausea, fatigue, headache, constipation, diarrhea, and vomiting.
The trial enrolled 670 CML-CP patients with resistance (n=497) or intolerance (n=173) to Gleevec who were randomized to one of four treatment arms: 100 mg once daily (n=167), 50 mg twice daily (n=168), 140 mg once daily (n=167), and 70 mg twice daily (n=168).
Tasigna is not approved for the treatment of newly diagnosed Ph+ CML-CP.
 
 
 
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