CRH-R1Corticotropin Releasing Hormone Receptor Type 1
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However, the effects of SPS or Topiramate on pituitary gene expression are not known; in the present paper, we examine the effects of SPS and Topiramate on mRNAs for GR, CRH-R1, or POMC (involved with production of ACTH).
Researchers say the new data "provide a functional validation for antagonism at CRH-R1 receptors as a mechanism for novel treatments aimed at relapse prevention in susceptible individuals," according to an NIAAA news release.