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CYP1A |
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Because CYP1A induction is activated by the aryl hydrocarbon receptor (AHR) pathway, as are most toxic responses to these compounds, we sought to determine the geographic extent of resistance to CYP1A mRNA induction by PCBs in the Hudson River tomcod population. Circulating lysozyme and hepatic CYP1A activities during a chronic dietary exposure to tributyltin (TBT) and 3,3', 4,4', 5-pentachlerobiphenyl (PCB-126) mixtures in channel catfish, Ictalurus punctatus. Although CYP1A for decades has been the most widely used biomarker for PAH exposure (Whyte et al. |
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