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Dependent on age, gender and the prevalence of further risk factors (smoking, previous cardiovascular event, family history of CVD, etc. Ten to 15 years after the trials ended, researchers found that the risk of a cardiovascular event was 25 to 30 percent lower in those who had been told to cut sodium. Merck's large randomized controlled clinical trials unequivocally do this, and plaintiff attorneys representing clients who took Vioxx can use that evidence to establish not only that the drug more likely than not caused an adverse cardiovascular event but also that with certain users--those with a history of symptomatic atherosclerotic disease--Vioxx was much more likely than any preexisting risk factor to have caused the event. |
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