| Acronym | Definition |
|---|
| COF | Council On Foundations |
| COF | Capital One Financial (stock symbol) |
| COF | Cradle of Filth (band) |
| COF | College Opportunity Fund |
| COF | Coefficient of Friction |
| COF | Chip on Film |
| COF | Certificate of Fitness |
| COF | Colleges of the Fenway (since 1996; Boston, Massachusetts) |
| COF | Chip-on-Flex |
| COF | Cost of Funds |
| COF | Course of Fire (pistol shooting sports) |
| COF | Chariots of Fire (movie) |
| COF | Columbus Orbital Facility |
| COF | Catholic Order of Foresters (Catholic fraternal insurance organization founded in 1883; Naperville, IL) |
| COF | Company Operations Facility |
| COF | Centro de Orientación Femenina (Guatemala) |
| COF | Cofidis - Credit par Telephone (Tour de France cycling sponsor) |
| COF | Canadian Orienteering Federation |
| COF | Classroom Of the Future |
| COF | Chain of Flowers (The Cure band fan site) |
| COF | Covalent Organic Framework (chemistry) |
| COF | Committee on Faculty |
| COF | College of Fisheries |
| COF | Complete Organic Fertilizer |
| COF | Council of Fellows |
| COF | Chamber of Fear |
| CoF | Cloak of Flames (Everquest game) |
| COF | Covered Offshore Facility |
| CoF | Customer Order Fulfillment |
| COF | Cost of Freight |
| COF | Construction Of Facility |
| COF | conduct of fire (US DoD) |
| COF | Central Operations Facility |
| COF | Certified Old Fart (Internet slang) |
| COF | Central Operating Facilities |
| COF | Civilian Objective Force |
| COF | Center of Flotation (hull design) |
| COF | Columbus Operating Facility |
| COF | Crazy Old Fart |
| CoF | Castle of Fun (WOTC message boards) |
| COF | Confirmation Order Form |
| COF | Church of Freethought |
| COF | Computing Operations Fundamentals (from BOFH) |
| COF | Channel Output Feedback |
| COF | Common Output File |
| COF | Commercial Organic Fertilizer (agriculture) |
| COF | Crabby Old Fart |
| COF | Certified Organic Farming (agriculture) |
| COF | Coloplast Ostomy Forum |
| COF | Canterbury Office Furniture (Douglas Furniture Ltd.; New Zealand) |
| COF | County Operated Facility |
| COF | City of the Future (various locations) |
| COF | Consumer Oriented Fabrics |
| CoF | Confidence of Fit (trend line) |
| COF | Comité d'Organisation des Fêtes (French: Holiday Organizing Committee) |
| COF | Conservatory of Flowers (San Francisco, CA) |
| CoF | Catalog of Fishes (database) |
| COF | Cavazzoni Orlando e Fratello (Italian ice cream) |