| Acronym | Definition |
|---|
| CDE | California Department of Education |
| CDE | Common Desktop Environment (Unix) |
| CDE | Colorado Department of Education |
| CDE | Certified Diabetes Educator |
| CDE | Centre for Development and Environment (Germany) |
| CDE | Continuing Dental Education |
| CDE | Coeur d'Alene Mines Corporation |
| CDE | Career Development Event |
| CDE | Convention relative aux droits de l'enfant |
| CDE | Combined Driving Event |
| CDE | Corporación Dominicana de Electricidad (Dominican Republic) |
| CDE | Consiglio d'Europa (Italian) |
| CDE | Committed Dose Equivalent |
| CDE | Convention des Nations Unies relative aux Droits de l'Enfant (French) |
| CDE | Cooperative Development Environment (Oracle) |
| CDE | Conference on Disarmament in Europe |
| CDE | Centro de Documentação Europeia (Portugal) |
| CDE | Cable Discharge Event |
| CDE | Concept Development and Experimentation |
| CDE | Compact Disk - Erasable |
| CDE | Complex Data Entry |
| CDE | Continuing Dispatch Education |
| CDE | Choline-Deficient Ethionine (supplemented diet) |
| CDE | Certified Data Educator |
| CDE | Common Duct Exploration (cholecystectomy) |
| CDE | Common Data Environment |
| CDE | Contents Directory Entry |
| CDE | collateral damage estimation (US DoD) |
| CDE | Collateral Damage Estimate |
| CDE | Center for Distance Education and Independent Learning (University of Alaska Fairbanks) |
| CDE | Call Detail Element (Cisco) |
| CDE | Caledonia Airport (Panama) |
| CDE | Conference on Electron Devices |
| CDE | Chemical Dry Etch (semiconductor manufacturing method) |
| CDE | Collaborative Decision Environment |
| CDE | Critical Driving Error (driving test) |
| CDE | Center for Directed Energy |
| CDE | Collective Dose Equivalent |
| CDE | Card Data Entry |
| CDE | Command Document End (ITU-T) |
| CDE | Core Deployable Element |
| CDE | Computer Design Engineer |
| CDE | Central De-Detector |
| CDE | Certificate in Data Education |
| CDE | Combat Development Engineering |
| CDE | Clinical Documentation Excellence |
| CDE | Children Designing & Engineering (curriculum development project) |
| CDE | City Document Exchange |
| CDE | Concept Design and Evaluation |
| CDE | Control Device Evaluation |
| CDE | Chemical Defense Equipment/Establishment |
| CDE | Claim Data Entry (insurance) |
| CDE | Configuration & Data Engineer |
| CDE | Clock Detect East |
| CDE | Collision Detect Electronics |
| CDE | Centre of Drug Evaluation (Drug Administration Law of SFDA of China) |
| CDE | Commercial Derivative Engine |