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A 53-year-old man presented with chronic otitis media in the right ear and a cholesteatoma in the right ear. All of the children attending each participating center were considered eligible unless they had an underlying chronic illness (immunologic diseases; neoplastic disorders; renal, cardiac, hepatic, or hematologic diseases; bronchodysplasia; Down syndrome; chronic otitis media with effusion) or even a mild acute upper or lower respiratory tract infection at the time of enrollment. Persistent fluid in the middle ear and chronic otitis media can reduce a child's heating at a time that is critical for speech and language development. |
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