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If there are any side effects in other animal or human cells, these will be also amplified by adjuvants, and thus not measured in chronic toxicity tests with the active ingredient alone. Registrants are generally required to conduct acute toxicity tests on formulated products, but they traditionally conduct chronic toxicity tests on the active ingredient alone. One key requirement is that the institution explore new applications for the Microtox Chronic Toxicity Test and report on the work, contributing to the technical literature on the technology. |
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