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The primary outcome measure was the ADCS version of the Clinical Global Impression of Change Scale (CGIC). In addition, tacrine-treated patients exhibited improvement in the Clinical Global Impression of Change, a subjective scale completed by both doctors and family members. In addition, at Weeks 8 and 10, antidepressant efficacy was evaluated using Clinical Global Impression Improvement (CGI-I) and Severity (CGI-S) scales (used by clinicians to assess improvement in a patient's MDD symptoms and the severity of their depression at various time points, respectively). |
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