| Acronym | Definition |
|---|
| COL | Column |
| COL | Colonel |
| COL | College |
| COL | Commonwealth Of Learning (RSA) |
| COL | Colorado (old style) |
| Col | Columbia (cinematography) |
| COL | Colombia |
| COL | Collections |
| COL | Collected |
| COL | Colonial |
| COL | Colored |
| COL | Complexity (gaming, Counter-Strike team) |
| COL | Colima (postcode, Mexico) |
| COL | Collateral |
| COL | Collagen |
| COL | Colossians |
| COL | Coliseum |
| COL | City Of London |
| COL | Columbus AFB (Columbus, MS) |
| COL | College of Letters (Wesleyan University) |
| COL | Combined Operating License |
| COL | Cause Of Loss (insurance) |
| COL | Computer Oriented Language |
| COL | Caldera Open Linux |
| COL | Colors of Love (band) |
| COL | Check Off List |
| COL | City of License (FCC) |
| COL | Certificate of License |
| COL | Common Output Level (US DoD) |
| COL | Chuckle out Loud |
| COL | Cartridge Overall Length |
| COL | Circle of Life Foundation |
| COL | Coastal Ocean Laboratory |
| CoL | College of Law of England and Wales |
| COL | Consortium for Open Learning |
| COL | Combat Off Load |
| COL | Communications-Oriented Language |
| COL | Chain of Leadership and Management |
| COL | Checkout Language (NASA) |
| COL | Career Opportunities List |
| COL | Contract Loan Program |
| COL | Clap Out Loud |
| COL | Clan Collision (Runescape game) |
| COL | Contracting Officer Letter |
| COL | Chip-On-Loadbeam technology |
| COL | Customer's Own Label (food production) |
| COL | Customer's Own Leather |
| COL | Contingency Operating Location |
| COL | Community of Learners (various organizations) |
| COL | Centre Ornithologique Lorrain (French: Lorraine Ornithological Center; Lorraine, France) |
| COL | Centre for Open Learning (various locations) |
| COL | Cost Of Living |
| COL | Crying Out Loud |
| COL | Counsel |
| COL | Committee on Legislation (various organizations) |
| COL | Comité Ouvrier du Logement (French: Housing Worker Committee) |
| COL | Cry Out Loud |
| COL | Council on Ocean Law |
| CoL | Catalogue of Life (species database) |